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Cyperenoic acid suppresses osteoclast differentiation and delays bone loss in a senile osteoporosis mouse model by inhibiting non-canonical NF-κB pathway

Cyperenoic acid is a terpenoid isolated from the root of a medicinal plant Croton crassifolius with a wide range of biological activities. In this study, the effects of cyperenoic acid on osteoclast differentiation were investigated both in vitro and in vivo using receptor activator of nuclear facto...

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Detalles Bibliográficos
Autores principales: Chawalitpong, Supatta, Chokchaisiri, Ratchanaporn, Suksamrarn, Apichart, Katayama, Shigeru, Mitani, Takakazu, Nakamura, Soichiro, Athamneh, Ahmad AI, Ritprajak, Patcharee, Leelahavanichkul, Asada, Aeimlapa, Ratchaneevan, Charoenphandhu, Narattaphol, Palaga, Tanapat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884777/
https://www.ncbi.nlm.nih.gov/pubmed/29618833
http://dx.doi.org/10.1038/s41598-018-23912-3