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Super enhancer inhibitors suppress MYC driven transcriptional amplification and tumor progression in osteosarcoma
Osteosarcoma is the most common primary bone sarcoma that mostly occurs in young adults. The causes of osteosarcoma are heterogeneous and still not fully understood. Identification of novel, important oncogenic factors in osteosarcoma and development of better, effective therapeutic approaches are i...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884797/ https://www.ncbi.nlm.nih.gov/pubmed/29644114 http://dx.doi.org/10.1038/s41413-018-0009-8 |