Super enhancer inhibitors suppress MYC driven transcriptional amplification and tumor progression in osteosarcoma

Osteosarcoma is the most common primary bone sarcoma that mostly occurs in young adults. The causes of osteosarcoma are heterogeneous and still not fully understood. Identification of novel, important oncogenic factors in osteosarcoma and development of better, effective therapeutic approaches are i...

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Detalles Bibliográficos
Autores principales: Chen, Demeng, Zhao, Zhiqiang, Huang, Zixin, Chen, Du-Chu, Zhu, Xin-Xing, Wang, Yi-Ze, Yan, Ya-Wei, Tang, Shaojun, Madhavan, Subha, Ni, Weiyi, Huang, Zhan-peng, Li, Wen, Ji, Weidong, Shen, Huangxuan, Lin, Shuibin, Jiang, Yi-Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884797/
https://www.ncbi.nlm.nih.gov/pubmed/29644114
http://dx.doi.org/10.1038/s41413-018-0009-8

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