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S-Nitrosoglutathione Reductase Underlies the Dysfunctional Relaxation to Nitric Oxide in Preterm Labor

Tocolytics show limited efficacy to prevent preterm delivery. In uterine smooth muscle cGMP accumulation following addition of nitric oxide (NO) has little effect on relaxation suggesting a role for protein S-nitrosation. In human myometrial tissues from women in labor at term (TL), or spontaneously...

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Detalles Bibliográficos
Autores principales: Barnett, Scott D., Smith, Christina R., Ulrich, Craig C., Baker, Josh E., Buxton, Iain L. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884813/
https://www.ncbi.nlm.nih.gov/pubmed/29618799
http://dx.doi.org/10.1038/s41598-018-23371-w