Metformin adapts its cellular effects to bioenergetic status in a model of metabolic dysfunction

Thermal injury induces a complex immunometabolic response, characterized by hyperglycemia, extensive inflammation and persistent hypermetabolism. It has been suggested that attenuation of the hypermetabolic response is beneficial for patient wellbeing. To that effect, metformin represents an attract...

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Detalles Bibliográficos
Autores principales: Auger, Christopher, Sivayoganathan, Thibacg, Abdullahi, Abdikarim, Parousis, Alexandra, Pang, Bo Wen, Jeschke, Marc G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884829/
https://www.ncbi.nlm.nih.gov/pubmed/29618839
http://dx.doi.org/10.1038/s41598-018-24017-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884829/
https://www.ncbi.nlm.nih.gov/pubmed/29618839
http://dx.doi.org/10.1038/s41598-018-24017-7

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