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Metformin adapts its cellular effects to bioenergetic status in a model of metabolic dysfunction
Thermal injury induces a complex immunometabolic response, characterized by hyperglycemia, extensive inflammation and persistent hypermetabolism. It has been suggested that attenuation of the hypermetabolic response is beneficial for patient wellbeing. To that effect, metformin represents an attract...
Autores principales: | Auger, Christopher, Sivayoganathan, Thibacg, Abdullahi, Abdikarim, Parousis, Alexandra, Pang, Bo Wen, Jeschke, Marc G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884829/ https://www.ncbi.nlm.nih.gov/pubmed/29618839 http://dx.doi.org/10.1038/s41598-018-24017-7 |
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