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Differential expression of microRNAs and other small RNAs in muscle tissue of patients with ALS and healthy age-matched controls

Amyotrophic lateral sclerosis is a late-onset disorder primarily affecting motor neurons and leading to progressive and lethal skeletal muscle atrophy. Small RNAs, including microRNAs (miRNAs), can serve as important regulators of gene expression and can act both globally and in a tissue-/cell-type-...

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Detalles Bibliográficos
Autores principales: Kovanda, Anja, Leonardis, Lea, Zidar, Janez, Koritnik, Blaž, Dolenc-Groselj, Leja, Ristic Kovacic, Stanislava, Curk, Tomaž, Rogelj, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884852/
https://www.ncbi.nlm.nih.gov/pubmed/29618798
http://dx.doi.org/10.1038/s41598-018-23139-2