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Differential expression of microRNAs and other small RNAs in muscle tissue of patients with ALS and healthy age-matched controls
Amyotrophic lateral sclerosis is a late-onset disorder primarily affecting motor neurons and leading to progressive and lethal skeletal muscle atrophy. Small RNAs, including microRNAs (miRNAs), can serve as important regulators of gene expression and can act both globally and in a tissue-/cell-type-...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884852/ https://www.ncbi.nlm.nih.gov/pubmed/29618798 http://dx.doi.org/10.1038/s41598-018-23139-2 |