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Exome Sequencing Identifies Genetic Variants Associated with Circulating Lipid Levels in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study (IRASFS)

Genome-wide association studies have identified numerous variants associated with lipid levels; yet, the majority are located in non-coding regions with unclear mechanisms. In the Insulin Resistance Atherosclerosis Family Study (IRASFS), heritability estimates suggest a strong genetic basis: low-den...

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Detalles Bibliográficos
Autores principales: Gao, Chuan, Tabb, Keri L., Dimitrov, Latchezar M., Taylor, Kent D., Wang, Nan, Guo, Xiuqing, Long, Jirong, Rotter, Jerome I., Watanabe, Richard M., Curran, Joanne E., Blangero, John, Langefeld, Carl D., Bowden, Donald W., Palmer, Nicholette D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884862/
https://www.ncbi.nlm.nih.gov/pubmed/29618726
http://dx.doi.org/10.1038/s41598-018-23727-2