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DPP6 Loss Impacts Hippocampal Synaptic Development and Induces Behavioral Impairments in Recognition, Learning and Memory

DPP6 is well known as an auxiliary subunit of Kv4-containing, A-type K(+) channels which regulate dendritic excitability in hippocampal CA1 pyramidal neurons. We have recently reported, however, a novel role for DPP6 in regulating dendritic filopodia formation and stability, affecting synaptic devel...

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Detalles Bibliográficos
Autores principales: Lin, Lin, Murphy, Jonathan G., Karlsson, Rose-Marie, Petralia, Ronald S., Gutzmann, Jakob J., Abebe, Daniel, Wang, Ya-Xian, Cameron, Heather A., Hoffman, Dax A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884885/
https://www.ncbi.nlm.nih.gov/pubmed/29651237
http://dx.doi.org/10.3389/fncel.2018.00084