Prion-Like Seeding of Misfolded α-Synuclein in the Brains of Dementia with Lewy Body Patients in RT-QUIC

The prion-like seeding of misfolded α-synuclein (αSyn) involved in the pathogenesis of Lewy body diseases (LBD) remains poorly understood at the molecular level. Using the real-time quaking-induced conversion (RT-QUIC) seeding assay, we investigated whether brain tissues from cases of dementia with...

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Detalles Bibliográficos
Autores principales: Sano, Kazunori, Atarashi, Ryuichiro, Satoh, Katsuya, Ishibashi, Daisuke, Nakagaki, Takehiro, Iwasaki, Yasushi, Yoshida, Mari, Murayama, Shigeo, Mishima, Kenichi, Nishida, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884914/
https://www.ncbi.nlm.nih.gov/pubmed/28550528
http://dx.doi.org/10.1007/s12035-017-0624-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884914/
https://www.ncbi.nlm.nih.gov/pubmed/28550528
http://dx.doi.org/10.1007/s12035-017-0624-1

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