IgA Targeting Human Immunodeficiency Virus-1 Envelope gp41 Triggers Antibody-Dependent Cellular Cytotoxicity Cross-Clade and Cooperates with gp41-Specific IgG to Increase Cell Lysis

The protective efficacy of human immunodeficiency virus-1 (HIV-1) antibodies (Abs) remains mostly correlated with their in vitro neutralizing activity engaging their Fab region. However, anti-HIV-1 Abs also mediate a broad array of Fc-mediated effector functions including Ab-dependent cellular cytot...

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Detalles Bibliográficos
Autores principales: Duchemin, Maxence, Khamassi, Marwa, Xu, Lin, Tudor, Daniela, Bomsel, Morgane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884934/
https://www.ncbi.nlm.nih.gov/pubmed/29651286
http://dx.doi.org/10.3389/fimmu.2018.00244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884934/
https://www.ncbi.nlm.nih.gov/pubmed/29651286
http://dx.doi.org/10.3389/fimmu.2018.00244

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