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Genetics Modulate Gray Matter Variation Beyond Disease Burden in Prodromal Huntington’s Disease

Huntington’s disease (HD) is a neurodegenerative disorder caused by an expansion mutation of the cytosine–adenine–guanine (CAG) trinucleotide in the HTT gene. Decline in cognitive and motor functioning during the prodromal phase has been reported, and understanding genetic influences on prodromal di...

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Detalles Bibliográficos
Autores principales: Liu, Jingyu, Ciarochi, Jennifer, Calhoun, Vince D., Paulsen, Jane S., Bockholt, H. Jeremy, Johnson, Hans J., Long, Jeffrey D., Lin, Dongdong, Espinoza, Flor A., Misiura, Maria B., Caprihan, Arvind, Turner, Jessica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884935/
https://www.ncbi.nlm.nih.gov/pubmed/29651271
http://dx.doi.org/10.3389/fneur.2018.00190