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Genetics Modulate Gray Matter Variation Beyond Disease Burden in Prodromal Huntington’s Disease
Huntington’s disease (HD) is a neurodegenerative disorder caused by an expansion mutation of the cytosine–adenine–guanine (CAG) trinucleotide in the HTT gene. Decline in cognitive and motor functioning during the prodromal phase has been reported, and understanding genetic influences on prodromal di...
Autores principales: | Liu, Jingyu, Ciarochi, Jennifer, Calhoun, Vince D., Paulsen, Jane S., Bockholt, H. Jeremy, Johnson, Hans J., Long, Jeffrey D., Lin, Dongdong, Espinoza, Flor A., Misiura, Maria B., Caprihan, Arvind, Turner, Jessica A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884935/ https://www.ncbi.nlm.nih.gov/pubmed/29651271 http://dx.doi.org/10.3389/fneur.2018.00190 |
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