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Identification of Unequally Represented Founder Viruses Among Tissues in Very Early SIV Rectal Transmission

Characterizing the transmitted/founder (T/F) viruses of multi-variant SIV infection may shed new light on the understanding of mucosal transmission. We intrarectally inoculated six Chinese rhesus macaques with a single high dose of SIVmac251 (3.1 × 10(4) TCID(50)) and obtained 985 full-length env se...

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Detalles Bibliográficos
Autores principales: Chen, Jian, Ren, Yanqin, Daharsh, Lance, Liu, Lu, Kang, Guobin, Li, Qingsheng, Wei, Qiang, Wan, Yanmin, Xu, Jianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884942/
https://www.ncbi.nlm.nih.gov/pubmed/29651274
http://dx.doi.org/10.3389/fmicb.2018.00557