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MYR1-Dependent Effectors Are the Major Drivers of a Host Cell’s Early Response to Toxoplasma, Including Counteracting MYR1-Independent Effects

The obligate intracellular parasite Toxoplasma gondii controls its host cell from within the parasitophorous vacuole (PV) by using a number of diverse effector proteins, a subset of which require the aspartyl protease 5 enzyme (ASP5) and/or the recently discovered MYR1 protein to cross the PV membra...

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Detalles Bibliográficos
Autores principales: Naor, Adit, Panas, Michael W., Marino, Nicole, Coffey, Michael J., Tonkin, Christopher J., Boothroyd, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885026/
https://www.ncbi.nlm.nih.gov/pubmed/29615509
http://dx.doi.org/10.1128/mBio.02401-17