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Conservation and Divergence in the Candida Species Biofilm Matrix Mannan-Glucan Complex Structure, Function, and Genetic Control

Candida biofilms resist the effects of available antifungal therapies. Prior studies with Candida albicans biofilms show that an extracellular matrix mannan-glucan complex (MGCx) contributes to antifungal sequestration, leading to drug resistance. Here we implement biochemical, pharmacological, and...

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Detalles Bibliográficos
Autores principales: Dominguez, Eddie, Zarnowski, Robert, Sanchez, Hiram, Covelli, Antonio S., Westler, William M., Azadi, Parastoo, Nett, Jeniel, Mitchell, Aaron P., Andes, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885036/
https://www.ncbi.nlm.nih.gov/pubmed/29615504
http://dx.doi.org/10.1128/mBio.00451-18