Cargando…
Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury
BACKGROUND: Traumatic Brain Injury (TBI) is a major cause of disability and mortality, to which there is currently no comprehensive treatment. Blood Brain Barrier (BBB) dysfunction is well documented in human TBI patients, yet the molecular mechanisms that underlie this neurovascular unit (NVU) path...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885297/ https://www.ncbi.nlm.nih.gov/pubmed/29618365 http://dx.doi.org/10.1186/s13024-018-0249-5 |