Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury

BACKGROUND: Traumatic Brain Injury (TBI) is a major cause of disability and mortality, to which there is currently no comprehensive treatment. Blood Brain Barrier (BBB) dysfunction is well documented in human TBI patients, yet the molecular mechanisms that underlie this neurovascular unit (NVU) path...

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Detalles Bibliográficos
Autores principales: Main, Bevan S., Villapol, Sonia, Sloley, Stephanie S., Barton, David J., Parsadanian, Maia, Agbaegbu, Chinyere, Stefos, Kathryn, McCann, Mondona S., Washington, Patricia M., Rodriguez, Olga C., Burns, Mark P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885297/
https://www.ncbi.nlm.nih.gov/pubmed/29618365
http://dx.doi.org/10.1186/s13024-018-0249-5

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