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Resveratrol-Induced Downregulation of NAF-1 Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine via the ROS/Nrf2 Signaling Pathways

NAF-1 (nutrient-deprivation autophagy factor-1), which is an outer mitochondrial membrane protein, is known to play important roles in calcium metabolism, antiapoptosis, and antiautophagy. Resveratrol, a natural polyphenolic compound, is considered as a potent anticancer agent. Nevertheless, the mol...

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Detalles Bibliográficos
Autores principales: Cheng, Liang, Yan, Bin, Chen, Ke, Jiang, Zhengdong, Zhou, Cancan, Cao, Junyu, Qian, Weikun, Li, Jie, Sun, Liankang, Ma, Jiguang, Ma, Qingyong, Sha, Huanchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885341/
https://www.ncbi.nlm.nih.gov/pubmed/29765509
http://dx.doi.org/10.1155/2018/9482018