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Relationship of SNP rs2645429 in Farnesyl-Diphosphate Farnesyltransferase 1 Gene Promoter with Susceptibility to Lung Cancer

BACKGROUND AND PURPOSE: The mevalonate pathway is one of the major metabolic pathways that use acetyl-CoA to produce sterols and isoprenoids. These compounds can be effective in the growth and development of tumors. One of the enzymes involved in the mevalonate pathway is FDFT1. Different variants o...

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Detalles Bibliográficos
Autores principales: Dehghani, Mehdi, Samani, Zahra, Abidi, Hassan, Manzouri, Leila, Mahmoudi, Reza, Hosseini Teshnizi, Saeed, Nikseresht, Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885393/
https://www.ncbi.nlm.nih.gov/pubmed/29765975
http://dx.doi.org/10.1155/2018/4863757