Cargando…

Relationship of SNP rs2645429 in Farnesyl-Diphosphate Farnesyltransferase 1 Gene Promoter with Susceptibility to Lung Cancer

BACKGROUND AND PURPOSE: The mevalonate pathway is one of the major metabolic pathways that use acetyl-CoA to produce sterols and isoprenoids. These compounds can be effective in the growth and development of tumors. One of the enzymes involved in the mevalonate pathway is FDFT1. Different variants o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dehghani, Mehdi, Samani, Zahra, Abidi, Hassan, Manzouri, Leila, Mahmoudi, Reza, Hosseini Teshnizi, Saeed, Nikseresht, Mohsen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885393/ https://www.ncbi.nlm.nih.gov/pubmed/29765975 http://dx.doi.org/10.1155/2018/4863757

Ejemplares similares

Roles of Farnesyl-Diphosphate Farnesyltransferase 1 in Tumour and Tumour Microenvironments
por: Ha, Nguyen Thi, et al.
Publicado: (2020)

Glucose starvation suppresses gastric cancer through targeting miR-216a-5p/Farnesyl-Diphosphate Farnesyltransferase 1 axis
por: Zhao, Ruiyang, et al.
Publicado: (2021)

Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors
por: Holland, Andrew J., et al.
Publicado: (2015)

Farnesyl Diphosphate Synthase Inhibitors from In Silico Screening
por: Lindert, Steffen, et al.
Publicado: (2013)

Farnesyl diphosphate synthase is important for the maintenance of glioblastoma stemness
por: Kim, Hee Yeon, et al.
Publicado: (2018)

Cloning and characterization of bifunctional enzyme farnesyl diphosphate/geranylgeranyl diphosphate synthase from Plasmodium falciparum
por: Jordão, Fabiana M, et al.
Publicado: (2013)

Concise synthesis of artemisinin from a farnesyl diphosphate analogue
por: Tang, Xiaoping, et al.
Publicado: (2018)

Deregulated expression and activity of Farnesyl Diphosphate Synthase (FDPS) in Glioblastoma
por: Abate, Mario, et al.
Publicado: (2017)

Plasmodium falciparum parasites overexpressing farnesyl diphosphate synthase/geranylgeranyl diphosphate synthase are more resistant to risedronate
por: Gabriel, Heloisa B, et al.
Publicado: (2018)

Farnesyl diphosphate synthase is involved in the resistance to zoledronic acid of osteosarcoma cells
por: Ory, B, et al.
Publicado: (2008)

Rapid Analysis of Protein Farnesyltransferase Substrate Specificity Using Peptide Libraries and Isoprenoid Diphosphate Analogues
por: Wang, Yen-Chih, et al.
Publicado: (2014)

Structure Conservation and Differential Expression of Farnesyl Diphosphate Synthase Genes in Euphorbiaceous Plants
por: Guo, Dong, et al.
Publicado: (2015)

Role of Cys73 in the thermostability of farnesyl diphosphate synthase from Geobacillus stearothermophilus
por: Samori, Petrus Yesaya, et al.
Publicado: (2017)

Functional characterization of a farnesyl diphosphate synthase from Dendrobium nobile Lindl
por: Gong, Daoyong, et al.
Publicado: (2022)

Protein farnesylation is upregulated in Alzheimer’s human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer’s model mice
por: Jeong, Angela, et al.
Publicado: (2021)

Biosynthesis of Squalene from Farnesyl Diphosphate in Bacteria: Three Steps Catalyzed by Three Enzymes
por: Pan, Jian-Jung, et al.
Publicado: (2015)

Inhibition of Coenzyme Qs Accumulation in Engineered Escherichia coli by High Concentration of Farnesyl Diphosphate
por: Samoudi, Mojtaba, et al.
Publicado: (2015)

Using Terpene Synthase Plasticity in Catalysis: On the Enzymatic Conversion of Synthetic Farnesyl Diphosphate Analogues
por: Hou, Anwei, et al.
Publicado: (2021)

Functional characterization and transcriptional activity analysis of Dryopteris fragrans farnesyl diphosphate synthase genes
por: Zhang, Dongrui, et al.
Publicado: (2023)

Cloning and Characterization of Farnesyl Diphosphate Synthase Gene Involved in Triterpenoids Biosynthesis from Poria cocos
por: Wang, Jianrong, et al.
Publicado: (2014)

Crystal Structure and Potential Head-to-Middle Condensation Function of a Z,Z-Farnesyl Diphosphate Synthase
por: Chan, Yueh-Te, et al.
Publicado: (2017)

Insights about the structure of farnesyl diphosphate synthase (FPPS) and the activity of bisphosphonates on the proliferation and ultrastructure of Leishmania and Giardia
por: Gadelha, Ana Paula R., et al.
Publicado: (2020)

Multi-Drug Resistance against Second-Line Medication and MicroRNA Plasma Level in Metastatic Breast Cancer Patients
por: Dehghani, Mehdi, et al.
Publicado: (2023)

Farnesyl diphosphate synthase regulated endothelial proliferation and autophagy during rat pulmonary arterial hypertension induced by monocrotaline
por: Jin, Tingting, et al.
Publicado: (2022)

Farnesyl diphosphate synthase, the target for nitrogen-containing bisphosphonate drugs, is a peroxisomal enzyme in the model system Dictyostelium discoideum
por: Nuttall, James M., et al.
Publicado: (2012)

Photosynthetic conversion of CO(2) to farnesyl diphosphate-derived phytochemicals (amorpha-4,11-diene and squalene) by engineered cyanobacteria
por: Choi, Sun Young, et al.
Publicado: (2016)

Sesquiterpene Synthase‐Catalysed Formation of a New Medium‐Sized Cyclic Terpenoid Ether from Farnesyl Diphosphate Analogues
por: Huynh, Florence, et al.
Publicado: (2018)

Enhanced Production of β-Caryophyllene by Farnesyl Diphosphate Precursor-Treated Callus and Hairy Root Cultures of Artemisia vulgaris L.
por: Balasubramani, Sundararajan, et al.
Publicado: (2021)

Bisphosphonate affects the behavioral responses to HCl by disrupting farnesyl diphosphate synthase in mouse taste bud and tongue epithelial cells
por: Oike, Asami, et al.
Publicado: (2022)

Biosynthesis of α-Bisabolol by Farnesyl Diphosphate Synthase and α-Bisabolol Synthase and Their Related Transcription Factors in Matricaria recutita L.
por: Tai, Yuling, et al.
Publicado: (2023)

Farnesyl diphosphate synthase promotes cell proliferation by regulating gene expression and alternative splicing profiles in HeLa cells
por: Wang, Lijuan, et al.
Publicado: (2023)

A cytosolic bifunctional geranyl/farnesyl diphosphate synthase provides MVA-derived GPP for geraniol biosynthesis in rose flowers
por: Conart, Corentin, et al.
Publicado: (2023)

Increased production of ganoderic acids by overexpression of homologous farnesyl diphosphate synthase and kinetic modeling of ganoderic acid production in Ganoderma lucidum
por: Fei, Yu, et al.
Publicado: (2019)

Rational design of Lepidoptera-specific insecticidal inhibitors targeting farnesyl diphosphate synthase, a key enzyme of the juvenile hormone biosynthetic pathway
por: Picard, Marie-Ève, et al.
Publicado: (2021)

Bacteria Are New Targets for Inhibitors of Human Farnesyltransferase
por: Weber, Lea, et al.
Publicado: (2021)

New targets for therapy in breast cancer: Farnesyltransferase inhibitors
por: Head, Julia, et al.
Publicado: (2004)

Engineering Protein Farnesyltransferase for Enzymatic Protein Labeling Applications
por: Dozier, Jonathan K., et al.
Publicado: (2014)

Effect of farnesyltransferase inhibitor on the function of mitochondria of Plasmodium falciparum
por: Ha, Young Ran, et al.
Publicado: (2012)

An overview on natural farnesyltransferase inhibitors for efficient cancer therapy
por: Dai, Xiaohan, et al.
Publicado: (2020)

Effect of farnesyltransferase inhibitors on SARS-CoV-2
por: Weber, Lea, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_nshmj4oikfhrapdnl8vdqaggt1