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TLR4-NF-κB Signal Involved in Depressive-Like Behaviors and Cytokine Expression of Frontal Cortex and Hippocampus in Stressed C57BL/6 and ob/ob Mice

Studies found that elevated levels of cytokines such as interleukin- (IL-) 1β, IL-6, and tumor necrosis factor-α (TNF-α) are closely associated with the pathogenesis of depression. Obesity providing a low-grade inflammation state was proposed to be implicated in susceptibility to depression in obesi...

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Detalles Bibliográficos
Autores principales: Wang, Yihe, Xu, Jingjing, Liu, Yuan, Li, Ziyang, Li, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885403/
https://www.ncbi.nlm.nih.gov/pubmed/29765402
http://dx.doi.org/10.1155/2018/7254016