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Deregulation of the spindle assembly checkpoint is associated with paclitaxel resistance in ovarian cancer

BACKGROUND: Ovarian cancer is the leading gynecologic cancer diagnosed in North America and because related symptoms are not disease specific, this often leads to late detection, an advanced disease state, and the need for chemotherapy. Ovarian cancer is frequently sensitive to chemotherapy at diagn...

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Detalles Bibliográficos
Autores principales: Chong, Taryne, Sarac, Amila, Yao, Cindy Q., Liao, Linda, Lyttle, Nicola, Boutros, Paul C., Bartlett, John M. S., Spears, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885411/
https://www.ncbi.nlm.nih.gov/pubmed/29618387
http://dx.doi.org/10.1186/s13048-018-0399-7