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Deregulation of the spindle assembly checkpoint is associated with paclitaxel resistance in ovarian cancer
BACKGROUND: Ovarian cancer is the leading gynecologic cancer diagnosed in North America and because related symptoms are not disease specific, this often leads to late detection, an advanced disease state, and the need for chemotherapy. Ovarian cancer is frequently sensitive to chemotherapy at diagn...
Autores principales: | Chong, Taryne, Sarac, Amila, Yao, Cindy Q., Liao, Linda, Lyttle, Nicola, Boutros, Paul C., Bartlett, John M. S., Spears, Melanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885411/ https://www.ncbi.nlm.nih.gov/pubmed/29618387 http://dx.doi.org/10.1186/s13048-018-0399-7 |
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