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Increased B3GALNT2 in hepatocellular carcinoma promotes macrophage recruitment via reducing acetoacetate secretion and elevating MIF activity

BACKGROUND: Hepatocellular carcinoma (HCC) ranks as the sixth most prevalent cancer and the third leading cause of tumor-related death, so it is urgently needed to discover efficient markers and targets for therapy. β-1,3-N-acetylgalactosaminyltransferase II (B3GALNT2) belongs to the β-1,3-glycosylt...

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Detalles Bibliográficos
Autores principales: Yang, Tianxiao, Wang, Yilin, Dai, Wenjuan, Zheng, Xixi, Wang, Jing, Song, Shushu, Fang, Lan, Zhou, Jiangfan, Wu, Weicheng, Gu, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885466/
https://www.ncbi.nlm.nih.gov/pubmed/29618368
http://dx.doi.org/10.1186/s13045-018-0595-3