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DNA Methylation in Osteoarthritis: Current Status and Therapeutic Implications

BACKGROUND: Primary Osteoarthritis (OA) is a multifactorial disease in which genetic factors are strongly associated with its development; however, recently it has been observed that epigenetic modifications are also involved in the pathogenesis of OA. DNA methylation is related to gene silencing, a...

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Detalles Bibliográficos
Autor principal: Miranda-Duarte, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885469/
https://www.ncbi.nlm.nih.gov/pubmed/29682093
http://dx.doi.org/10.2174/1874312901812010037