Exploring the mechanism of the Pd-catalyzed spirocyclization reaction: a combined DFT and experimental study

The mechanism of the palladium-catalyzed spirocyclization of acrylamides has been investigated by density functional theory and experimental studies. The results support a mechanistic pathway that proceeds via oxidative addition, intramolecular carbopalladation, C–H bond activation, and migratory in...

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Detalles Bibliográficos
Autores principales: Franzoni, Ivan, Yoon, Hyung, García-López, José-Antonio, Poblador-Bahamonde, Amalia Isabel, Lautens, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885594/
https://www.ncbi.nlm.nih.gov/pubmed/29675193
http://dx.doi.org/10.1039/c7sc04709f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885594/
https://www.ncbi.nlm.nih.gov/pubmed/29675193
http://dx.doi.org/10.1039/c7sc04709f

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