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The vinylogous Catellani reaction: a combined computational and experimental study
In the presence of 5 mol% Pd(OAc)(2), 1 equiv. of norbornene, and K(2)CO(3), the reaction of 4-iodo-2-quinolones with tertiary o-bromobenzylic alcohols produced the desired benzopyran-fused 2-quinolones in moderate to high yields. A Catellani-type mechanism involving vinylic C–H cleavage is proposed...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885779/ https://www.ncbi.nlm.nih.gov/pubmed/29675164 http://dx.doi.org/10.1039/c7sc04265e |