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Sub-nanosecond tryptophan radical deprotonation mediated by a protein-bound water cluster in class II DNA photolyases

Class II DNA photolyases are flavoenzymes occurring in both prokaryotes and eukaryotes including higher plants and animals. Despite considerable structural deviations from the well-studied class I DNA photolyases, they share the main biological function, namely light-driven repair of the most common...

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Detalles Bibliográficos
Autores principales: Müller, Pavel, Ignatz, Elisabeth, Kiontke, Stephan, Brettel, Klaus, Essen, Lars-Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885780/
https://www.ncbi.nlm.nih.gov/pubmed/29675165
http://dx.doi.org/10.1039/c7sc03969g