GMPR: A robust normalization method for zero-inflated count data with application to microbiome sequencing data

Normalization is the first critical step in microbiome sequencing data analysis used to account for variable library sizes. Current RNA-Seq based normalization methods that have been adapted for microbiome data fail to consider the unique characteristics of microbiome data, which contain a vast numb...

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Detalles Bibliográficos
Autores principales: Chen, Li, Reeve, James, Zhang, Lujun, Huang, Shengbing, Wang, Xuefeng, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885979/
https://www.ncbi.nlm.nih.gov/pubmed/29629248
http://dx.doi.org/10.7717/peerj.4600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885979/
https://www.ncbi.nlm.nih.gov/pubmed/29629248
http://dx.doi.org/10.7717/peerj.4600

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