AZA-MS: a novel multiparameter mass spectrometry method to determine the intracellular dynamics of azacitidine therapy in vivo

The cytidine analogue, 5-azacytidine (AZA; 5-AZA-cR), is the primary treatment for myelodysplastic syndrome and chronic myelomonocytic leukaemia. However, only ~50% of treated patients will respond to AZA and the drivers of AZA resistance in vivo are poorly understood. To better understand the intra...

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Detalles Bibliográficos
Autores principales: Unnikrishnan, A, Vo, A N Q, Pickford, R, Raftery, M J, Nunez, A C, Verma, A, Hesson, L B, Pimanda, J E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886051/
https://www.ncbi.nlm.nih.gov/pubmed/29249821
http://dx.doi.org/10.1038/leu.2017.340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886051/
https://www.ncbi.nlm.nih.gov/pubmed/29249821
http://dx.doi.org/10.1038/leu.2017.340

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