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MiR-29b antagonizes the pro-inflammatory tumor-promoting activity of multiple myeloma-educated dendritic cells

Dendritic cells (DCs) have a key role in regulating tumor immunity, tumor cell growth and drug resistance. We hypothesized that multiple myeloma (MM) cells might recruit and reprogram DCs to a tumor-permissive phenotype by changes within their microRNA (miRNA) network. By analyzing six different miR...

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Detalles Bibliográficos
Autores principales: Botta, C, Cucè, M, Pitari, M R, Caracciolo, D, Gullà, A, Morelli, E, Riillo, C, Biamonte, L, Gallo Cantafio, M E, Prabhala, R, Mignogna, C, Di Vito, A, Altomare, E, Amodio, N, Di Martino, M T, Correale, P, Rossi, M, Giordano, A, Munshi, N C, Tagliaferri, P, Tassone, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886056/
https://www.ncbi.nlm.nih.gov/pubmed/29158557
http://dx.doi.org/10.1038/leu.2017.336