Zebrafish cdc6 hypomorphic mutation causes Meier-Gorlin syndrome-like phenotype

Cell Division Cycle 6 (Cdc6) is a component of pre-replicative complex (preRC) forming on DNA replication origins in eukaryotes. Recessive mutations in ORC1, ORC4, ORC6, CDT1 or CDC6 of the preRC in human cause Meier-Gorlin syndrome (MGS) that is characterized by impaired post-natal growth, short st...

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Detalles Bibliográficos
Autores principales: Yao, Likun, Chen, Jing, Wu, Xiaotong, Jia, Shunji, Meng, Anming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886151/
https://www.ncbi.nlm.nih.gov/pubmed/28985365
http://dx.doi.org/10.1093/hmg/ddx305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886151/
https://www.ncbi.nlm.nih.gov/pubmed/28985365
http://dx.doi.org/10.1093/hmg/ddx305

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