De novo mutations implicate novel genes in systemic lupus erythematosus

The omnigenic model of complex disease stipulates that the majority of the heritability will be explained by the effects of common variation on genes in the periphery of core disease pathways. Rare variant associations, expected to explain far less of the heritability, may be enriched in core diseas...

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Detalles Bibliográficos
Autores principales: Pullabhatla, Venu, Roberts, Amy L, Lewis, Myles J, Mauro, Daniele, Morris, David L, Odhams, Christopher A, Tombleson, Philip, Liljedahl, Ulrika, Vyse, Simon, Simpson, Michael A, Sauer, Sascha, de Rinaldis, Emanuele, Syvänen, Ann-Christine, Vyse, Timothy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886157/
https://www.ncbi.nlm.nih.gov/pubmed/29177435
http://dx.doi.org/10.1093/hmg/ddx407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886157/
https://www.ncbi.nlm.nih.gov/pubmed/29177435
http://dx.doi.org/10.1093/hmg/ddx407

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