The mitochondrial metallochaperone SCO1 maintains CTR1 at the plasma membrane to preserve copper homeostasis in the murine heart

SCO1 is a ubiquitously expressed, mitochondrial protein with essential roles in cytochrome c oxidase (COX) assembly and the regulation of copper homeostasis. SCO1 patients present with severe forms of early onset disease, and ultimately succumb from liver, heart or brain failure. However, the inhere...

Descripción completa

Detalles Bibliográficos
Autores principales: Baker, Zakery N, Jett, Kimberly, Boulet, Aren, Hossain, Amzad, Cobine, Paul A, Kim, Byung-Eun, El Zawily, Amr M, Lee, Ling, Tibbits, Glen F, Petris, Michael J, Leary, Scot C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886179/
https://www.ncbi.nlm.nih.gov/pubmed/28973536
http://dx.doi.org/10.1093/hmg/ddx344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886179/
https://www.ncbi.nlm.nih.gov/pubmed/28973536
http://dx.doi.org/10.1093/hmg/ddx344

Ejemplares similares