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Behavioral and transcriptomic analysis of Trem2-null mice: not all knockout mice are created equal
It is clear that innate immune system status is altered in numerous neurodegenerative diseases. Human genetic studies have demonstrated that triggering receptor expressed in myeloid cells 2 (TREM2) coding variants have a strong association with Alzheimer’s disease (AD) and other neurodegenerative di...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886290/ https://www.ncbi.nlm.nih.gov/pubmed/29040522 http://dx.doi.org/10.1093/hmg/ddx366 |