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Mouse Models for Drug Discovery. Can New Tools and Technology Improve Translational Power?
The use of mouse models in biomedical research and preclinical drug evaluation is on the rise. The advent of new molecular genome-altering technologies such as CRISPR/Cas9 allows for genetic mutations to be introduced into the germ line of a mouse faster and less expensively than previous methods. I...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886322/ https://www.ncbi.nlm.nih.gov/pubmed/28053071 http://dx.doi.org/10.1093/ilar/ilw021 |