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Cross-reactivity of anti-HMGB1 antibodies for HMGB2

HMGB1 and HMGB2 are DNA-interacting proteins but can also have extracellular actions during inflammation. Despite their relatively high homology, they may have distinct roles, making it essential to be able to differentiate between the two. Here we examine the specificity of five commercially-availa...

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Detalles Bibliográficos
Autores principales: Davies, Jessica E., Apta, Bonita H.R., Harper, Matthew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886380/
https://www.ncbi.nlm.nih.gov/pubmed/29453955
http://dx.doi.org/10.1016/j.jim.2018.02.006