Ultrafiltered recombinant AAV8 vector can be safely administered in vivo and efficiently transduces liver

Viral vectors are extensively purified for use in biomedical research, in order to separate biologically active virus particles and to eliminate production related impurities that are assumed to be detrimental to the host. For recombinant adeno-associated virus (rAAV) vectors this is typically accom...

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Detalles Bibliográficos
Autores principales: Kleven, Mark D., Gomes, Michelle M., Wortham, Aaron M., Enns, Caroline A., Kahl, Christoph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886455/
https://www.ncbi.nlm.nih.gov/pubmed/29621273
http://dx.doi.org/10.1371/journal.pone.0194728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886455/
https://www.ncbi.nlm.nih.gov/pubmed/29621273
http://dx.doi.org/10.1371/journal.pone.0194728

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