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Ultrafiltered recombinant AAV8 vector can be safely administered in vivo and efficiently transduces liver
Viral vectors are extensively purified for use in biomedical research, in order to separate biologically active virus particles and to eliminate production related impurities that are assumed to be detrimental to the host. For recombinant adeno-associated virus (rAAV) vectors this is typically accom...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886455/ https://www.ncbi.nlm.nih.gov/pubmed/29621273 http://dx.doi.org/10.1371/journal.pone.0194728 |