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DNA strand-exchange patterns associated with double-strand break-induced and spontaneous mitotic crossovers in Saccharomyces cerevisiae

Mitotic recombination can result in loss of heterozygosity and chromosomal rearrangements that shape genome structure and initiate human disease. Engineered double-strand breaks (DSBs) are a potent initiator of recombination, but whether spontaneous events initiate with the breakage of one or both D...

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Detalles Bibliográficos
Autores principales: Hum, Yee Fang, Jinks-Robertson, Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886692/
https://www.ncbi.nlm.nih.gov/pubmed/29579095
http://dx.doi.org/10.1371/journal.pgen.1007302