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Molecular events leading to HPV-induced high grade neoplasia

Cervical cancer is initiated by high-risk types of the human papillomavirus (hrHPV) and develops via precursor stages, called cervical intraepithelial neoplasia (CIN). High-grade CIN lesions are considered true precancerous lesions when the viral oncogenes E6 and E7 are aberrantly expressed in the d...

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Detalles Bibliográficos
Autores principales: Wilting, Saskia M., Steenbergen, Renske D.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886901/
https://www.ncbi.nlm.nih.gov/pubmed/29074190
http://dx.doi.org/10.1016/j.pvr.2016.04.003