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Polygenic risk score: use in migraine research
BACKGROUND: The latest Genome-Wide Association Study identified 38 genetic variants associated with migraine. In this type of studies the significance level is very difficult to achieve (5 × 10(− 8)) due to multiple testing. Thus, the identified variants only explain a small fraction of the genetic...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Milan
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887014/ https://www.ncbi.nlm.nih.gov/pubmed/29623444 http://dx.doi.org/10.1186/s10194-018-0856-0 |