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Polygenic risk score: use in migraine research

BACKGROUND: The latest Genome-Wide Association Study identified 38 genetic variants associated with migraine. In this type of studies the significance level is very difficult to achieve (5 × 10(− 8)) due to multiple testing. Thus, the identified variants only explain a small fraction of the genetic...

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Detalles Bibliográficos
Autores principales:	Chalmer, Mona Ameri, Esserlind, Ann-Louise, Olesen, Jes, Hansen, Thomas Folkmann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Milan 2018
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887014/ https://www.ncbi.nlm.nih.gov/pubmed/29623444 http://dx.doi.org/10.1186/s10194-018-0856-0

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