A modular synthetic route to size-defined immunogenic Haemophilus influenzae b antigens is key to the identification of an octasaccharide lead vaccine candidate

The first glycoconjugate vaccine using isolated glycans was licensed to protect children from Haemophilus influenzae serotype b (Hib) infections. Subsequently, the first semisynthetic glycoconjugate vaccine using a mixture of antigens derived by polymerization targeted the same pathogen. Still, a de...

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Detalles Bibliográficos
Autores principales: Baek, J. Y., Geissner, A., Rathwell, D. C. K., Meierhofer, D., Pereira, C. L., Seeberger, P. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887106/
https://www.ncbi.nlm.nih.gov/pubmed/29675174
http://dx.doi.org/10.1039/c7sc04521b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887106/
https://www.ncbi.nlm.nih.gov/pubmed/29675174
http://dx.doi.org/10.1039/c7sc04521b

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