Functional Redundancy of DICER Cofactors TARBP2 and PRKRA During Murine Embryogenesis Does Not Involve miRNA Biogenesis

Several in vitro studies have suggested that canonical microRNA (miRNA) biogenesis requires the DICER cofactors TARBP2 and PRKRA for processing of pre-miRNAs to mature miRNAs. To investigate the roles of TARBP2 and PRKRA in miRNA biogenesis in vivo, and to determine possible functional redundancy, w...

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Detalles Bibliográficos
Autores principales: Pullagura, Sri Ramulu N., Buaas, Bill, Gray, Nichelle, Krening, Lindsey C., Srivastava, Anuj, Braun, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887145/
https://www.ncbi.nlm.nih.gov/pubmed/29467169
http://dx.doi.org/10.1534/genetics.118.300791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887145/
https://www.ncbi.nlm.nih.gov/pubmed/29467169
http://dx.doi.org/10.1534/genetics.118.300791

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