The interplay of BDNF-TrkB with NMDA receptor in propofol-induced cognition dysfunction: Mechanism for the effects of propofol on cognitive function

BACKGROUND: The aim of the present study was to verify whether propofol impaired learning and memory through the interplay of N-methyl-D-aspartate (NMDA) receptor with brain-derived neurotrophic factor (BDNF)-tyrosine kinase B (TrkB) signaling pathway. METHODS: 120 Sprague-Dawley (SD) rats were rand...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Junfei, Wang, Fang, Zhang, Jun, Li, Jianfeng, Ma, Li, Dong, Tieli, Zhuang, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887174/
https://www.ncbi.nlm.nih.gov/pubmed/29621970
http://dx.doi.org/10.1186/s12871-018-0491-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887174/
https://www.ncbi.nlm.nih.gov/pubmed/29621970
http://dx.doi.org/10.1186/s12871-018-0491-y

Ejemplares similares