High-affinity and selective detection of pyrophosphate in water by a resorcinarene salt receptor

Pyrophosphate (PPi) is a byproduct of DNA and RNA synthesis, and abnormal levels are indicative of disease. We report the high-affinity binding of PPi in water by N-alkyl ammonium resorcinarene chloride receptors. Experimental analysis using (1)H and (31)P NMR, isothermal titration calorimetry, mass...

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Detalles Bibliográficos
Autores principales: Beyeh, Ngong Kodiah, Díez, Isabel, Taimoory, S. Maryamdokht, Meister, Daniel, Feig, Andrew I., Trant, John F., Ras, Robin H. A., Rissanen, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887233/
https://www.ncbi.nlm.nih.gov/pubmed/29675184
http://dx.doi.org/10.1039/c7sc05167k