A novel restriction endonuclease GlaI for rapid and highly sensitive detection of DNA methylation coupled with isothermal exponential amplification reaction

Sensitive and accurate detection of site-specific DNA methylation is of critical significance for early diagnosis of human diseases, especially cancers. Herein, for the first time we employ a novel methylation-dependent restriction endonuclease GlaI to detect site-specific DNA methylation in a highl...

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Detalles Bibliográficos
Autores principales: Sun, Yueying, Sun, Yuanyuan, Tian, Weimin, Liu, Chenghui, Gao, Kejian, Li, Zhengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887237/
https://www.ncbi.nlm.nih.gov/pubmed/29675182
http://dx.doi.org/10.1039/c7sc04975g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887237/
https://www.ncbi.nlm.nih.gov/pubmed/29675182
http://dx.doi.org/10.1039/c7sc04975g

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