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A novel restriction endonuclease GlaI for rapid and highly sensitive detection of DNA methylation coupled with isothermal exponential amplification reaction

Sensitive and accurate detection of site-specific DNA methylation is of critical significance for early diagnosis of human diseases, especially cancers. Herein, for the first time we employ a novel methylation-dependent restriction endonuclease GlaI to detect site-specific DNA methylation in a highl...

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Detalles Bibliográficos
Autores principales:	Sun, Yueying, Sun, Yuanyuan, Tian, Weimin, Liu, Chenghui, Gao, Kejian, Li, Zhengping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2017
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887237/ https://www.ncbi.nlm.nih.gov/pubmed/29675182 http://dx.doi.org/10.1039/c7sc04975g

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